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This situation is expected to increase the nephrotoxicity severity caused by cisplatin accumulation in the proximal tubules of the kidney 43,49,56,57

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C., Sati D., Bhatt P., Samant M

Ngamukote S, Yanagisawa M, Ariga T, Ando S, Yu RK (2007) Developmental changes of glycosphingolipids and expression of glycogenes in mouse brains

The less mature immune system observed in neonates enables a more balanced regenerative reaction within the mammalian heart through activating cardiomyocyte proliferation and angiogenesis via interleukin-6/signal transducer and activator of transcription signaling 41,42